Below you'll find a list of all posts that have been tagged as “cbd”
Cannabidiol (CBD) Found to Reduce Seizure Frequency in Phase III Trial The oral administration of CBD (cannabidiol) reduces seizure frequency in children with intractable epilepsy, according to placebo-controlled, randomized trial data published in The New England Journal of Medicine. In this double-blind, placebo-controlled trial, they randomly assigned 120 children and young adults with the Dravet syndrome and drug-resistant seizures to …
CBD directly interacts with various ion channels to confer a therapeutic effect. CBD, for example, binds to TRPV1 receptors, which also function as ion channels. TRPV1 is known to mediate pain perception, inflammation and body temperature. TRPV is the technical abbreviation for “transient receptor potential cation channel subfamily V.” TRPV1 is one of several dozen TRP (pronounced “trip”) receptor variants …
Allosteric Modulator Australian scientists report that CBD acts as a “positive allosteric modulator” of the GABA-A receptor. In other words, CBD interacts with the GABA-A receptor in a way that enhances the receptor’s binding affinity for its principal endogenous agonist, gamma-Aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. The sedating effects of Valium …
CBD Reuptake Inhibitor How does CBD, an exogenous plant compound, get inside a human cell to bind to a nuclear receptor? First it has to pass through the cell membrane by hitching a ride with a fatty acid binding protein (FABP), which chaperones various lipid molecules into the cell’s interior. These intracellular transport molecules also escort tetrahydrocannabinol (THC) and the …
Joy Beckerman, president of Hemp Ace International, a Seattle-based consulting firm, teaches a class for law students on “The Curious Legal Status of CBD and Industrial Hemp-Derived Cannabinoids.” An industrial hemp entrepreneur and advocate for the past 25 years, Beckerman recognizes that cannabidiol has played a key role in jump-starting the creation of new infrastructure for hemp’s vast oilseed and …
Chronic Pain If you’re at all familiar with cannabis or cannabidiol (CBD), you’re probably well aware of its use in the medical realm as an option for the treatment of pain. The analgesic benefits of CBD via the body’s endocannabinoid system have been well-researched, with numerous clinical trials supporting claims of its effectiveness for pain. But those who suffer with …
CBD an Antipsychotic? Studies have shown CBD may relieve psychotic symptoms associated with schizophrenia, according to research by University of Cologne in Germany. Schizophrenia affects about 1.1 percent of the population, or approximately 2.4 million adults in the United States. CBD continues to surprise researchers with the variety of common health benefits it provides. An increasing number of scientists, physicians …
CBD vs THC It’s 420 so I thought it was a good day to cover the real differences between CBD and THC. I’m a huge CBD evangelist but that’s not to say I don’t enjoy and love the experience of ingesting THC. I’m self employed and I live in a recreational state where I can legally buy marijuana and smoke …
Insomnia One of the few side effects of CBD is tiredness, that’s what puts the “chill” in Just Chill Products but for many, it’s what they seek out in the natural herb. Since pharmaceuticals for aiding sleep pose risk for addiction and leave you feeling groggy the next day, it’s best to go the safe route with non-habit forming CBD. …
Scientists at the Cajal Institute used animal models and cell cultures to find that CBD reversed inflammatory responses and served as durable protection from the effects of multiple sclerosis. Mice with 10 days of CBD treatment had superior motor skills and showed progression in their condition. Using this information, researchers concluded that CBD has the potential ability to reduce various …
